In 1813, the Sultan gave Thassos to the viceroy of Egypt Muhammad Ali, as a reward. The viceroy was good to the people of Thassos, because he was born in Kavala and was raised in a village of the island with a Greek family.
Thassos was occupied by the Turks in 1455, two years after the fall of Constantinople, when Mohamed II organized an expedition against the Aenos peninsula, while at the same time he sent ten ships to Thassos, Samothrace and Imvros.
When Constantinople was occupied by the Franks, Thassos was given to Enrico Dandolo, doge of Venece (1204). From then on, a number of conquerors cast an envious eye on the beautiful island.
Byzantine historians regarding Thassos in that period of time. The Christian religion was made known to the island in 52 AD, when Apostle Paul traveled from Troy (Asia Minor today) to Neapolis (Kavala today).
After the entry in the 2nd Athenian Confederacy in 377 BC, the Thassians used the support of Athens to extend their influence in the main land. In 357 or 340 BC, King Philippos of Macedonia expands in the neighbouring area. Under the kingship of the Macedonians, Thassos maintains a part of its autonomy.
According to Greek mythology, the first inhabitant and founder of the island, was a namesake man called Thassos. Thassos was either the son or the grandson of Aginoras, King of Phoenicia, who turned up in Thassos while trying to find Europa who had been kidnapped by Zeus in virtue of his passionate love.
During the period of the 1821 revolution, Thassos breathed a short period of freedom, when the Greeks arrived to the island and the tzormpatzis was set head of the revolutionary movement. The Turks were defeated and expelled to Kavala. However, this did not last long, because the fear of pirates led the Thassians to seek help from the passa of Thessalonici.